:root{--paper:#fafaf7;--ink:#222b29;--muted:#737b75;--line:#dcded7;--accent:#456353;--wash:#eef1ea}*{box-sizing:border-box}body{margin:0;background:var(--paper);color:var(--ink);font-family:Arial,sans-serif;font-size:14px;line-height:1.6}a{color:inherit;text-underline-offset:4px}button,input,select,textarea{font:inherit;color:inherit}button,a,input,select,summary,textarea{outline-offset:4px}button{cursor:pointer;border:1px solid var(--line);background:transparent;padding:10px 15px;border-radius:2px}button:hover{border-color:var(--accent);background:var(--wash)}button:disabled{cursor:wait;opacity:.5}button.primary{background:var(--accent);border-color:var(--accent);color:#fff}button.secondary{background:#fff}h1,h2{font-family:Georgia,'Times New Roman',serif;font-weight:400;line-height:1.15}h1{font-size:54px;letter-spacing:-2px;margin:12px 0}h2{font-size:27px;margin:10px 0 20px}p{margin:10px 0 16px}.eyebrow,.step{font-size:10px;letter-spacing:1.6px;color:var(--muted)}.muted{color:var(--muted)}.small{font-size:12px}.mono,pre,textarea{font-family:Consolas,monospace}.full{width:100%}[hidden]{display:none!important}header{display:flex;justify-content:space-between;align-items:center;padding:20px 4%;border-bottom:1px solid var(--line);gap:20px}.brand{text-decoration:none;font-weight:bold;letter-spacing:.5px}.brand span{font-weight:normal;color:var(--muted)}.workspace{max-width:1560px;margin:auto;padding:35px 4%}.page-heading{display:flex;justify-content:space-between;align-items:center;gap:20px}.intro{font-size:16px;color:var(--muted)}.scope-note{border-left:2px solid var(--accent);padding:6px 15px;color:#5a665e;margin:20px 0 35px;font-size:13px}.layout{display:grid;grid-template-columns:310px minmax(0,1fr);gap:46px}aside{border-right:1px solid var(--line);padding-right:28px}aside section{padding:0 0 22px;margin-bottom:22px;border-bottom:1px solid var(--line)}.step{margin-top:0;margin-bottom:16px}label{display:block;font-size:12px;margin:15px 0 6px}input,select,textarea{width:100%;padding:9px 10px;border:1px solid var(--line);background:white;border-radius:2px;min-width:0}input[type=file]{font-size:11px;padding:8px}textarea{resize:vertical;font-size:12px;line-height:1.5}.inline{display:flex;gap:8px}.inline input{flex:1;width:100px}.two-col{display:grid;grid-template-columns:1fr 1fr;gap:12px}.tabs{display:flex;border-bottom:1px solid var(--line);margin-bottom:15px}.tabs button{border:0;flex:1;font-size:12px;border-radius:0;border-bottom:2px solid transparent}.tabs button.active{border-bottom-color:var(--accent);color:var(--accent)}#gene-info,#reference-status{overflow-wrap:anywhere;margin-top:10px}.text-button{border:0;padding:4px 0;text-decoration:underline;font-size:12px}.status{font-size:12px;overflow-wrap:anywhere;min-height:24px}.status.error{color:#9b3d30}.empty{padding:42px 12px 55px;min-height:335px}.empty-rule{height:1px;width:70px;background:var(--accent);margin-bottom:26px}.empty p{color:var(--muted)}.empty-steps{display:flex;gap:30px;font-size:11px;color:var(--muted);margin-top:35px}.methods{border-top:1px solid var(--line);margin-top:35px;padding-top:26px;max-width:950px}.methods h2{font-size:23px}.methods p:not(.step){font-size:13px;color:#58615b}.source-links{display:flex;flex-wrap:wrap;gap:20px;font-size:12px}.result-heading{display:flex;justify-content:space-between;gap:15px;align-items:baseline}.downloads{display:flex;gap:15px;white-space:nowrap;font-size:12px}#result-target{font-size:12px;overflow-wrap:anywhere}.metrics{display:grid;grid-template-columns:repeat(3,1fr);border-block:1px solid var(--line);margin:20px 0}.metric{padding:15px;border-right:1px solid var(--line)}.metric:last-child{border:0}.metric strong{display:block;font-size:26px;font-weight:normal}.metric span{font-size:11px;color:var(--muted)}.reference-note{font-size:12px;background:var(--wash);padding:12px 15px;overflow-wrap:anywhere}.table-tools{display:flex;flex-wrap:wrap;align-items:center;gap:10px;margin:22px 0 12px}.table-tools label{margin:0}.table-tools select{width:auto;font-size:11px}.table-scroll{max-height:480px;overflow:auto;border-block:1px solid var(--line)}table{border-collapse:separate;border-spacing:0;width:100%;font-size:11px;text-align:left;white-space:nowrap}th{position:sticky;top:0;background:var(--paper);font-weight:normal;color:var(--muted);z-index:1}td,th{padding:13px 10px;border-bottom:1px solid var(--line)}td:nth-child(2){font-family:Consolas,monospace;letter-spacing:.4px}tbody tr:hover{background:var(--wash);cursor:pointer}tbody tr.selected{background:#e7ece3}.row-button{border:0;padding:0;text-decoration:underline;font-size:11px}.detail{border:1px solid var(--line);padding:22px;margin-top:25px;overflow-wrap:anywhere}.detail h3{font-size:14px;font-weight:normal;margin:0 0 16px}.duplex{font-family:Consolas,monospace;font-size:14px;line-height:1.8;letter-spacing:2px;overflow:auto;white-space:pre;margin:15px 0;padding:15px;background:var(--wash)}.detail ul{padding-left:18px;font-size:12px}details{margin-top:20px;font-size:12px}summary{cursor:pointer;padding:10px 0}pre{white-space:pre-wrap;overflow-wrap:anywhere;background:#f0f1ec;padding:15px;font-size:11px;max-height:350px;overflow:auto}footer{margin-top:50px;border-top:1px solid var(--line);padding:20px 0;color:var(--muted);font-size:11px}.portal{min-height:100vh;display:grid;place-items:center}.portal-main{max-width:800px;width:100%;padding:40px}.portal h1{font-size:44px;margin-bottom:40px}.project-links{display:grid;grid-template-columns:1fr 1fr;gap:20px;margin-bottom:30px}.project-links a{position:relative;display:flex;flex-direction:column;text-decoration:none;border:1px solid var(--line);padding:30px;min-height:190px;transition:background .15s}.project-links a:hover{background:var(--wash);border-color:var(--accent)}.project-links span{font-size:11px;color:var(--muted)}.project-links strong{font-family:Georgia,serif;font-size:32px;font-weight:normal;margin:10px 0}.project-links small{font-size:12px;color:var(--muted)}.project-links b{position:absolute;right:25px;top:30px;font-weight:normal}@media(max-width:1000px){.layout{grid-template-columns:275px minmax(0,1fr);gap:25px}aside{padding-right:20px}.result-heading{display:block}.empty-steps{gap:12px}h1{font-size:44px}}@media(max-width:720px){header .small{display:none}.workspace{padding:25px 20px}.layout{display:block}aside{border-right:0;padding-right:0;margin-bottom:40px}.page-heading{align-items:flex-start}.page-heading button{max-width:145px;font-size:12px}.empty{min-height:240px;padding:20px 0}.project-links{grid-template-columns:1fr}.portal-main{padding:25px}.portal h1{font-size:36px}.metrics .metric{padding:12px 8px}.source-links{gap:12px}}

.project-links b{width:24px;height:24px;display:grid;place-items:center;font-family:Arial,sans-serif;font-size:20px;line-height:1}
.example-actions{display:flex;flex-wrap:wrap;gap:10px;justify-content:flex-end}.paired-example{margin:20px 0 28px;padding:24px;border:1px solid var(--rule,var(--line));background:var(--surface,var(--paper))}.paired-example h2{font:400 28px/1.4 var(--serif,Georgia)}.paired-example>p{font-size:14px;line-height:1.8}.rna-pair-views{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:20px}.rna-pair-views article{min-width:0}.rna-pair-views h3{font-size:17px;font-weight:500}.rna-pair-views p{font-size:12px;line-height:1.8}.rna-structure{display:flex;gap:5px}.rna-structure span{flex:1;padding:10px 7px;background:var(--accent-soft,var(--wash));border:1px solid var(--rule,var(--line));text-align:center}.rna-structure .intron{background:transparent;border-style:dashed}.paired-example textarea{font:12px/1.7 var(--mono,monospace);resize:vertical}.paired-example select{max-width:600px}@media(max-width:720px){.example-actions{justify-content:flex-start}.rna-pair-views{grid-template-columns:1fr}.paired-example{padding:16px}.page-heading{flex-wrap:wrap;gap:18px}.page-heading .example-actions button{max-width:none}}

#paired-sources{overflow-wrap:anywhere}.paired-summary p{font-size:13px;line-height:1.8}.paired-summary .table-scroll{max-height:none}