*{box-sizing:border-box}.research-console{margin:0;--paper:#f5f5f0;--surface:#fff;--ink:#172e32;--ink-2:#5a6d70;--accent:#126b68;--accent-ink:#115b59;--accent-soft:#e2eeea;--rule:#d9e1dc;--rule-2:#b9c9c2;background:var(--paper);color:var(--ink);font:14px/1.7 var(--sans)}.skip-link{position:absolute;top:-100px;left:20px;background:var(--surface);padding:10px;z-index:10}.skip-link:focus{top:10px}.console-heading{max-width:1480px;margin:auto;padding:35px 32px 28px;display:flex;align-items:start;justify-content:space-between;gap:25px;background:none;border:0}.workspace-label{font:9px/1.7 var(--mono);letter-spacing:.08em;color:var(--ink-2);margin:0 0 15px}.console-heading h1{font:400 43px/1.15 var(--serif);letter-spacing:-.035em;margin:0 0 15px}.console-heading>div>p:last-child{font-size:12px;max-width:720px;color:var(--ink-2);margin:0}.console-heading>button{padding:7px 12px;background:transparent;border:1px solid var(--rule-2);border-radius:0;font:10px 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var(--rule);min-width:0}.stat:first-child{padding-left:0;border:0}.lab,.sub{display:block;font-size:9px;color:var(--ink-2)}.num{font:28px/1.4 var(--serif);display:block;color:var(--ink)}.context-note{padding:16px 18px;background:var(--accent-soft);border-left:2px solid var(--accent);font-size:11px;line-height:1.8;margin:22px 0;color:var(--ink)}.context-note strong{font-weight:600}.sect{margin-top:25px}.sect h3{font:400 23px/1.3 var(--serif);margin:0 0 13px}.sect p{font-size:12px;margin:10px 0;line-height:1.8}.muted,.note{color:var(--ink-2)}.note{font-size:11px;line-height:1.8;margin:16px 0}.kv{display:grid;grid-template-columns:190px minmax(0,1fr);gap:10px 20px;font-size:11px;line-height:1.8}.kv dt{color:var(--ink-2)}.kv dd{margin:0;overflow-wrap:anywhere}.workspace-actions{display:flex;align-items:center;flex-wrap:wrap;gap:12px;margin:26px 0 10px}.btn,.workspace-actions>button{display:inline-block;background:var(--accent);color:#fff;border:1px solid var(--accent);border-radius:0;padding:10px 14px;font:11px/1.6 var(--sans);text-decoration:none;cursor:pointer}.btn.ghost,.workspace-actions>.ghost{background:transparent;color:var(--accent-ink);border-color:var(--rule-2)}.workspace-actions>.btn:hover{color:#fff;background:var(--accent-ink)}.workspace-actions>.ghost:hover{color:var(--accent-ink);background:var(--accent-soft)}.data-scroll{max-width:100%;overflow:auto;scrollbar-width:thin;max-height:600px;overscroll-behavior:contain;border:1px solid var(--rule);margin:18px 0}.raw-table{width:100%;min-width:650px;border-collapse:collapse;white-space:normal}.raw-table th,.raw-table td{padding:11px 12px;vertical-align:top;text-align:left;border-bottom:1px solid var(--rule);font:11px/1.8 var(--sans)}.raw-table th{font-weight:500;background:var(--accent-soft);color:var(--ink);position:static}.raw-table thead th{position:sticky;top:0}.raw-table td small{display:block;font-size:9px;color:var(--ink-2);margin-top:4px}.raw-table td:last-child{min-width:190px}.qc-label{font-size:9px;line-height:1.7;color:var(--ink-2)}.qc-consistent{color:var(--accent-ink)}.field{margin:18px 0}.field label,.scenario-form label:not(.assumption-check){display:block;font:10px/1.7 var(--mono);color:var(--ink-2);margin-bottom:8px}.field input,.field select,.method-details select{width:100%;border:1px solid var(--rule-2);border-radius:0;padding:9px 10px;background:var(--surface);color:var(--ink);font:12px var(--sans);min-width:0}.method-details{padding:14px 0;border-block:1px solid var(--rule);font-size:11px;margin:22px 0}.method-details summary{cursor:pointer;color:var(--accent-ink);padding:4px 0}.method-details p{color:var(--ink-2);line-height:1.8}.method-details .btn{margin-top:13px}.method-details label{display:block;margin-bottom:7px}.grid2{display:grid;grid-template-columns:minmax(0,1fr) minmax(0,1fr);gap:0 20px}.assumption-check{display:flex;gap:12px;align-items:flex-start;font-size:11px;line-height:1.8;margin:18px 0}.assumption-check input{width:17px;height:17px;flex:none;margin:2px 0 0;accent-color:var(--accent)}.scenario-empty{padding:15px 0;font-size:11px;color:var(--ink-2)}.scenario-output{padding:20px;background:var(--accent-soft);margin-top:25px}.scenario-output>p:last-child{font-size:10px;overflow-wrap:anywhere}.scenario-output .kv{font-size:11px}.evidence-entry{padding:20px 0;border-top:1px solid var(--rule)}.evidence-entry>div{display:flex;justify-content:space-between;gap:20px;align-items:baseline}.evidence-entry h3{font:400 23px/1.3 var(--serif);margin:0}.evidence-entry p{font-size:12px;line-height:1.8;margin:12px 0 0}.evidence-entry .muted{font-size:11px}.evidence-label{font:8px/1.6 var(--mono);padding-left:9px;border-left:2px solid var(--rule-2);color:var(--ink-2)}.status-example,.status-platform{border-color:var(--accent);color:var(--accent-ink)}.status-context,.status-unresolved{border-color:#9b7837}.source-link{display:block;font-size:10px;line-height:1.8;margin-top:10px}.next-checks{padding-left:22px;font-size:12px}.next-checks li{padding:9px 0;border-bottom:1px solid var(--rule)}#export-text{display:block;width:100%;height:540px;resize:vertical;max-width:100%;padding:16px;border:1px solid var(--rule);border-radius:0;background:var(--paper);font:11px/1.8 var(--mono);white-space:pre-wrap;margin-top:12px}#copy-status{font-size:10px;color:var(--accent-ink)}.console-footer{max-width:1480px;margin:auto;padding:22px 32px;border-top:1px solid var(--ink);display:flex;align-items:center;justify-content:space-between;gap:25px;font:9px/1.7 var(--mono);color:var(--ink-2)}.console-footer p{margin:0}.console-footer a{white-space:nowrap}.console-noscript{padding:20px;margin:auto;max-width:1480px}[hidden]{display:none!important}
@media(prefers-color-scheme:dark){:root:not([data-theme=light]) .research-console{--paper:#101c20;--surface:#17272b;--ink:#e8ede6;--ink-2:#a4b5b5;--accent:#8aceb7;--accent-ink:#a1dfcd;--accent-soft:#1d3636;--rule:#2b4143;--rule-2:#577673}}
:root[data-theme=dark] .research-console{--paper:#101c20;--surface:#17272b;--ink:#e8ede6;--ink-2:#a4b5b5;--accent:#8aceb7;--accent-ink:#a1dfcd;--accent-soft:#1d3636;--rule:#2b4143;--rule-2:#577673}
@media(max-width:1050px){.console-layout{grid-template-columns:210px minmax(0,1fr);gap:20px}.pane{padding:20px}.kv{grid-template-columns:150px 1fr}.tab{padding:13px 12px;font-size:11px}.statrow{grid-template-columns:1fr 1fr;gap:15px}.stat:nth-child(3){border:0;padding-left:0}}
@media(max-width:760px){.console-heading{padding:27px 20px 22px;flex-wrap:wrap}.console-heading h1{font-size:35px}.console-layout{display:block;padding:0 20px 30px}.rail{position:static;margin-bottom:24px}.genes{grid-template-columns:repeat(4,1fr)}.gbtn{padding:9px 6px}.gn{font-size:18px}.gc{font-size:8px}.rail h2:not(:first-child){margin-top:18px}.vlist{display:flex;max-height:130px;overflow:auto;flex-wrap:wrap;gap:5px}.vbtn{width:auto;flex:1 1 130px;border:1px solid var(--rule);padding:8px}.rail-note{display:none}.tabs{width:100%}.pane{padding:20px 15px}.ptitle{font-size:26px}.grid2{grid-template-columns:1fr;gap:0}.kv{grid-template-columns:1fr;gap:4px}.kv dt{margin-top:10px}.kv dd{padding-bottom:4px}.evidence-entry>div{flex-wrap:wrap;gap:9px}.evidence-entry h3{font-size:22px}.context-note{padding:14px}.console-footer{padding:20px;flex-wrap:wrap;font-size:8px}.console-footer p{order:3;flex-basis:100%}.workspace-actions .btn{font-size:10px}.scenario-output{padding:15px}}
@media(prefers-color-scheme:dark){:root:not([data-theme=light]) .research-console .btn:not(.ghost),:root:not([data-theme=light]) .research-console .fchip[aria-pressed=true],:root:not([data-theme=light]) .research-console .workspace-actions>button:not(.ghost){color:#102c29}}
:root[data-theme=dark] .research-console .btn:not(.ghost),:root[data-theme=dark] .research-console .fchip[aria-pressed=true]{color:#102c29}
@media print{.site-nav,.console-heading>button,.rail,.tabs,.workspace-actions{display:none}.console-layout{display:block;padding:0}.research-panel{border:0}.pane[hidden]{display:block!important}.data-scroll{overflow:visible;max-height:none}.research-console{--paper:white;--surface:white;--ink:black;--ink-2:#333;--rule:#ddd}}

.traffic-grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:20px;margin-top:25px}.traffic-card{padding:20px 16px;border:1px solid var(--rule);min-width:0}.traffic-card h3{font:400 21px/1.3 var(--serif);margin:0 0 20px;min-height:55px}.traffic-housing{display:flex;flex-direction:column;gap:11px;width:78px;background:#172e32;border:1px solid #47635f;padding:15px;border-radius:20px;margin:0 auto 22px}.traffic-lamp{display:block;aspect-ratio:1;border-radius:50%;background:#334b4c;border:1px solid #56706b;opacity:.45}.traffic-lamp.is-on{opacity:1;border-color:transparent}.lamp-red.is-on{background:#e1685c;box-shadow:0 0 0 4px #e1685c1c}.lamp-yellow.is-on{background:#efbd54;box-shadow:0 0 0 4px #efbd541c}.lamp-green.is-on{background:#6cc79f;box-shadow:0 0 0 4px #6cc79f1c}.traffic-card>p{font-size:11px;line-height:1.8;margin:12px 0}.traffic-card .traffic-status{font:500 12px/1.6 var(--sans);border-bottom:1px solid var(--rule);padding-bottom:12px}.traffic-card .source-link{font-size:9px}.color-red{color:var(--gap)}.color-yellow{color:var(--warn)}.color-green{color:var(--accent-ink)}
@media(max-width:1000px){.traffic-grid{grid-template-columns:1fr}.traffic-card h3{min-height:0}.traffic-housing{flex-direction:row;width:180px;padding:12px;border-radius:25px}.traffic-lamp{flex:1;min-width:0}}
/* Clear research navigation and readable data labels. */
.console-heading{padding-block:30px}.console-heading h1{font-size:38px}.console-heading>div>p:last-child{font-size:15px;max-width:780px}.console-layout{grid-template-columns:270px minmax(0,1fr);gap:24px}.rail{background:var(--surface);border:1px solid var(--rule);padding:18px}.rail h2{font:600 14px/1.5 var(--sans);text-transform:none;letter-spacing:0}.step-number{display:inline-grid;place-items:center;width:24px;height:24px;margin-right:7px;border:1px solid var(--rule-2);color:var(--accent-ink);font:12px var(--mono)}.gbtn{padding:12px 10px}.gn{font-size:25px}.gc{font-size:11px}.variant-picker{margin-top:24px}.variant-picker>summary{font-size:14px;font-weight:600;cursor:pointer;list-style:none}.variant-picker>summary::after{content:'+';float:right;color:var(--accent-ink)}.variant-picker[open]>summary::after{content:'−'}.variant-picker>summary>span:last-child{display:block;margin:6px 0 0 33px;font:12px var(--mono);color:var(--ink-2)}.picker-help{font-size:12px;line-height:1.7;color:var(--ink-2)}.fchip{font:12px/1.5 var(--sans);padding:7px 9px}.search-label{font:12px var(--sans)}#vsearch{font-size:14px;padding:11px}.vcount,.rail-note{font:11px/1.8 var(--sans)}.vlist{max-height:290px}.vbtn{padding:13px 8px;font-size:13px}.mm{font:11px var(--sans)}.current-selection{display:flex;align-items:center;justify-content:space-between;gap:18px;padding:22px 24px;background:var(--accent-soft);border-bottom:1px solid var(--rule-2)}.current-selection>div{min-width:0}.selection-label{display:block;font-size:12px;color:var(--ink-2)}#current-variant{display:block;font:500 24px/1.5 var(--mono);overflow-wrap:anywhere}#current-gene-name{display:block;font-size:13px;color:var(--ink-2)}#change-variant{flex-shrink:0;background:var(--surface);border:1px solid var(--rule-2);padding:9px 12px;font-size:12px;cursor:pointer}.tabs{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));overflow:visible;border:0}.tab{display:flex;align-items:start;gap:9px;text-align:left;white-space:normal;min-width:0;padding:15px 12px;border:1px solid var(--rule);border-top:0;border-left:0;line-height:1.5}.tab-number{font:11px var(--mono);padding-top:3px;color:var(--ink-2)}.tab-copy{display:flex;flex-direction:column;gap:4px;min-width:0}.tab-copy strong{font-size:13px;font-weight:600}.tab-copy small{font-size:11px;color:var(--ink-2)}.tab[aria-selected=true]{box-shadow:inset 0 -3px var(--accent)}.stage-guide{font-size:13px;line-height:1.8;color:var(--ink-2);padding:16px 24px;margin:0;border-bottom:1px solid var(--rule);background:var(--paper)}.pane{padding:26px}.pane .plead,.pane .note,.pane .muted,.sect p{font-size:14px;line-height:1.85}.lab,.sub{font-size:11px;line-height:1.6}.statrow .num{font-size:30px}.kv{font-size:13px}.field label{font-size:13px}.field select{font-size:13px}.frequency-help{margin:22px 0;padding:16px 18px;background:var(--accent-soft);border:1px solid var(--rule)}.frequency-help summary{cursor:pointer;font-size:14px;font-weight:600}.frequency-help p,.frequency-help dd{font-size:13px;line-height:1.8}.frequency-help dl{display:grid;grid-template-columns:110px minmax(0,1fr);gap:8px 16px}.frequency-help dt{font-size:13px;font-weight:600}.frequency-help dd{margin:0}.frequency-value{font:600 15px/1.7 var(--mono);white-space:nowrap}.raw-table td,.raw-table th{font-size:12px;line-height:1.75}.raw-table small{font-size:11px;line-height:1.7}.qc-label{font-size:11px}.evidence-entry p,.traffic-card>p{font-size:13px}.evidence-entry h3,.traffic-card h3{font-size:22px}.source-link{font-size:12px}.workspace-actions button,.workspace-actions a{font-size:13px}.tab:focus-visible,.gbtn:focus-visible,.vbtn:focus-visible,summary:focus-visible{outline:3px solid var(--accent);outline-offset:2px}
@media(max-width:1100px){.console-layout{grid-template-columns:235px minmax(0,1fr);gap:16px;padding-inline:20px}.tabs{grid-template-columns:repeat(2,minmax(0,1fr))}}
@media(max-width:850px){.console-layout{display:block;padding:0 16px 30px}.rail{position:static;margin-bottom:18px;padding:16px}.genes{grid-template-columns:repeat(4,minmax(0,1fr))}.gbtn{padding:10px 7px}.gn{font-size:22px}.gc{font-size:10px}.variant-picker{margin-top:16px}.variant-picker>summary>span:last-child{display:inline;margin-left:8px}.rail-note{margin-top:14px;padding-top:10px}.vlist{max-height:230px}.current-selection{padding:18px;gap:10px}.console-heading{padding:25px 18px}.console-heading h1{font-size:34px}.console-heading>div>p:last-child{font-size:14px}.stage-guide{padding:14px 18px}.pane{padding:20px 18px}.ptitle{font-size:28px}.tab{padding:12px 9px}.tab-copy strong{font-size:12px}.tab-copy small{font-size:10px}#current-variant{font-size:19px}#change-variant{font-size:11px;padding:8px}.frequency-help dl{grid-template-columns:1fr;gap:3px}.frequency-help dd{margin-bottom:8px}}
@media(max-width:380px){.genes{grid-template-columns:repeat(2,minmax(0,1fr))}.current-selection{align-items:start;flex-direction:column}.tab-number{display:none}}
@media print{.current-selection,.stage-guide{display:none}}